Here's an overview of skin whitening agents, including both drugs and cosmetic products commonly used to treat hyperpigmentation and even skin tone:
1. Drugs for Skin Whitening
These are pharmaceutical-grade treatments that are typically more potent and used under medical supervision:
a. Hydroquinone
b. Retinoids (e.g., Tretinoin, Retinol)
c. Azelaic Acid
d. Tranexamic Acid
2. Cosmetic Products for Skin Whitening
These include over-the-counter (OTC) products that are less potent but safer for general use:
a. Arbutin
b. Kojic Acid
c. Vitamin C (Ascorbic Acid)
d. Niacinamide (Vitamin B3)
3. Natural and Plant-Based Agents
These are sought after for their perceived safety and minimal side effects:
a. Licorice Extract (Glabridin)
b. Green Tea Extract (EGCG)
4. Combination Formulations
Combining various active ingredients often yields better results:
- Hydroquinone and Retinoids: Enhanced lightening and cell turnover.
- Vitamin C with Vitamin E and Ferulic Acid: Stabilizes and enhances antioxidant effects.
- Kojic Acid with AHAs (like glycolic acid): Improves penetration and exfoliation for better results.
5. Safety Considerations
- Sun Protection: Crucial when using any skin-lightening agents to prevent increased photosensitivity and protect results.
- Patch Testing: Recommended for agents like kojic acid or high-potency products to avoid irritation.
- Regulatory Concerns: Some agents like hydroquinone face restrictions in various regions due to potential side effects.